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To prevent an upset stomach, administer the drug together with your dog's meal. By working with a physician, getting these more general mental issues manageable can reduce PE. Other reports have found that there is often a dysfunction inside the connection between "the temporal pole in the limbic system, the basal ganglia, and also the orbitofrontal cortex" (Stein & Ludik, 1998, p. It could be frightening to get blissfully sleeping, in the midst of an pleasant dream, and hear the sounds of the loud explosion vibrate through your head. However, the client did still experience self-consciousness and although his obsessive compulsive behaviour decreased, he still spent many hours a day obsessing over appearance.